Product Profile

Product NameIntegrin beta 4 (phospho Tyr1526) antibodyAntibody TypePrimary AntibodiesProduct descriptionRabbit Polyclonal antibody to Integrin beta 4 (phospho Tyr1526)Integrins are heterodimers comprised of alpha ａnd beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha ａnd beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, ａnd transduced signals that regulate gene expression ａnd cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit ａnd is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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ImmunogenKLH conjugated Synthesised phosphopeptide derived from mouse ITGB4 around the phosphorylation site of Tyr1526

Key Feature

ClonalityPolyclonalIsotypeIgGHost SpeciesRabbitTested ApplicationsWB

WB(1:100-500):

Species ReactivityMouse

Predicted ReactivityGuinea pig, PigConcentration1 mg/ml (Please refer to the vial label for the specific concentration)PurificationAffinity purified

Target Information

Gene Synonymsphospho ITGB4 (phospho Tyr1526) Tyr1526

phospho ITGB4 (phospho Tyr1526)

CD104

ITGB4 (phospho Tyr1526) Y1526 phospho

ITGB4 (phospho Tyr1526) Tyr1526 phospho

ITGB4 (phospho Tyr1526) phospho Y1526

ITGB4 (phospho Tyr1526) (Phospho Y1526)

Phospho ITGB4 (

More TargetIntegrin beta 4 (phospho Tyr1526)Tissue Specificityphospho-ITGB4(Tyr1526)

Application

Application WB analysis of mouse heart (lane 1) ａnd mouse brain (lane 2) lysates using ITGB4 (phospho Tyr1526) antibody at a dilution of 1:200.

Application NotesWB(1:100-500):

Additional Information

FormLiquidStorage InstructionsKeep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.Storage BufferAqueous buffered solution containing 100ug/ml BSA, 50% glycerol ａnd less than 0.09% sodium azide.

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